From the desk of Lewis S. Blevins, Jr. MD – A 52-year-old man was referred to the pituitary clinic for further evaluation of hypercortisolism. Has had an unspecified weight gain and hypertension. His blood pressure
From the desk of Lewis S. Blevins, Jr. M.D. cofounder – The regulation of aldosterone secretion is rather complex. It is a beautiful system that involves multiple steps and organs. I will try to
I first learned of this condition in 1990 during my fellowship training in endocrinology at The Johns Hopkins Hospital. I
An Opinion Editorial from Jorge D. Faccinetti – Co-founder and Chief Editor – In today’s publishing landscape, one thing is clear: artificial intelligence and machine learning are advancing at dizzying speeds. Keeping up with these developments and understanding their true impact on our work and lives has become increasingly challenging.
A few highlights: Cushing syndrome refers to the classical appearance of hypercortisolism as described by Dr. Harvey Cushing. Many patients with hypercortisolism or pathologic cortisol secretion do not appear cushingoid but instead have one or
Listen to this fascinating discussion of adrenal Cushing’s or hypercortisolism as Dr. Lewis Blevins walks us through the disease’s characteristics, biochemistry, and treatment options. In the talk, he focuses on different conditions, including adrenal adenomas, adrenal cancer, adrenal hyperplasia, and other related diseases like Carney Complex and McCune-Albright syndrome.
Learn about management and approaches to stress doses of steroids and adjustments in patients with adrenal insufficiency.
There is growing interest in the use of cortisol pumps to treat patients with adrenal insufficiency, though most physicians in the US lack experience in this area. Dr. Lewis Blevins caught up with Dr. Naila Goldenberg at The Endocrine Society Meeting in San Francisco, California, in July 2025.
From Dr. Lewis Blevins. What constitutes a normal test result? In most endocrine assays, it is a population of supposedly normal individuals that defines the upper and lower limits of normal. Take the mean, and
From Dr. Lewis Blevins. There is a lot of confusion as to what constitutes a replacement dose of a steroid hormone for patients with hypopituitarism. The textbooks are wrong and, if we took doses they
From Lewis S Blevins Jr, MD – I define hypopituitarism as the partial or the complete deficiency of one or more anterior pituitary hormones. As a result of how this all works, patients can have
From Lewis Blevins, MD – Cortisol is a stress hormone. Thus, physical or psychic stress can elevate cortisol levels in normal persons. Depression and alcoholism can elevate cortisol levels and cause what is called pseudo-