From Lewis Blevins MD, Adrenal World News cofounder, medical director of the California Center for Pituitary disorders and professor of neurological surgery at UCSF – I always suggest that a diagnosis of PsuedoCushing’s syndrome be
For Professionals
This section offers content specifically designed for physicians and other healthcare professionals wishing to learn and share experiences with pituitary disease.
Connshing Syndrome: A 35-Year-Old Hunch, a Patient’s Instinct, and a Diagnosis That Changed Everything
February 27, 2026
From the desk of Lewis Blevins, MD, AWN cofounder – I have a vague recollection of considering the possibility of the coexistence of primary aldosteronism and hypercortisolism in adrenal hyperplasia during my fellowship in Endocrinology
The Cushing Syndrome Conundrum: Diagnosing and Managing a Silent Driver of Hypertension
February 12, 2026
In this recent Medscape InDiscussion podcast Dr. Marwah Abdalla welcomes PWN’s Dr. Lewis Blevins to talk about secondary hypertension. This episode focuses on Cushing syndrome, an often overlooked cause of secondary hypertension. We’ll discuss why
When ‘Normal’ Isn’t Normal: The Problem with Adrenal Hyperplasia Diagnosis
February 11, 2026
Hyperplasia is a term that implies an increase in the number of normal cells in a gland or other tissue. Sometimes the cells themselves are also enlarged, or hypertrophic. Tissues can be hypertrophic without being
Hypercortisolism due to Adrenal Hyperplasia
January 27, 2026
From the desk of Lewis S. Blevins, Jr. MD – A 52-year-old man was referred to the pituitary clinic for further evaluation of hypercortisolism. Has had an unspecified weight gain and hypertension. His blood pressure
When Genetics Matter Most: Understanding Hereditary in Pheochromocytomas and Paragangliomas
January 9, 2026
Genetic Syndromes Association with Pheochromocytomas and Paragangliomas From Jennifer Perkins, MD, MBA, Co-director of UCSF’s endocrine neoplasia program, Executive Medical Director ambulatory, and PWN contributor – Pheochromocytomas (PCCs) are catecholamine-secreting tumors arising from chromaffin cells
ACTH Stimulation Tests: Demystified (Well, partially.)
December 16, 2025
Adrenocorticotrophic hormone, ACTH, drives cortisol production by the adrenal glands. It should come as no surprise that administration of ACTH can be used to test for insufficient adrenal function. Keep in mind that measures of
Aldosterone Deficiency: Clinical Pearls from Years of Experience
December 15, 2025
Mineralocorticoid Replacement Therapy From the desk of Lewis S. Blevins Jr., M.D. – Treatment of partial and complete aldosterone deficiency seems to be an arena where inexperienced physicians miss the mark more often than not.
Dr. Naila Goldenberg speaks about Adrenal Insufficiency and her experiences with cortisol pumps
September 30, 2025
There is growing interest in the use of cortisol pumps to treat patients with adrenal insufficiency, though most physicians in the US lack experience in this area. Dr. Lewis Blevins caught up with Dr. Naila Goldenberg at The Endocrine Society Meeting in San Francisco, California, in July 2025.
Idiopathic isolated central adrenal insufficiency
September 28, 2025
From the desk of Lewis S. Blevins, Jr. M.D. PWN cofounder – Idiopathic isolated central adrenal insufficiency remains a mystery. I’ve seen several patients with this condition in my career. I first learned about it