In today’s podcast, Crinetics co-founders Dr. Scott Struthers and Dr. Steve Betz share their views and experiences in drug discovery and development, revealing what it really takes to bring a new medication from concept to patients.
Cushing’s Syndrome
Cushing’s syndrome is a disorder that occurs when your body makes too much of the hormone cortisol over a long period of time. Cortisol is sometimes called the “stress hormone” because it helps your body respond to stress.
Cushing’ Syndrome. What would you do next? How doctors reason through data.
January 21, 2026
From Lewis S. Blevins, Jr. MD, – I’ve taken care of a patient for a number of years. She has had central hypothyroidism and growth and deficiency presumed due to a partial empty sella. Recently,
The Diagnostic Gap: Why Most Adrenal Masses Go Untested
January 7, 2026
A commentary on adrenal masses by Dr. Lewis Blevins, AWN cofounder – My experience with adrenal disorders is that radiologists often miss things. Some adrenal nodules are not even reported on CT scans of the
ACTH Stimulation Tests: Demystified (Well, partially.)
December 16, 2025
Adrenocorticotrophic hormone, ACTH, drives cortisol production by the adrenal glands. It should come as no surprise that administration of ACTH can be used to test for insufficient adrenal function. Keep in mind that measures of
The Evolution of our Understanding of the Nuances of Pathologic Cortisol Secretion.
October 2, 2025
A few highlights: Cushing syndrome refers to the classical appearance of hypercortisolism as described by Dr. Harvey Cushing. Many patients with hypercortisolism or pathologic cortisol secretion do not appear cushingoid but instead have one or
Adrenal Cushing’s: a conversation
October 1, 2025
Listen to this fascinating discussion of adrenal Cushing’s or hypercortisolism as Dr. Lewis Blevins walks us through the disease’s characteristics, biochemistry, and treatment options. In the talk, he focuses on different conditions, including adrenal adenomas, adrenal cancer, adrenal hyperplasia, and other related diseases like Carney Complex and McCune-Albright syndrome.
When It Looks Like Cushing’s But It Isn’t
September 29, 2025
We are delighted to welcome Dr. Leena Shahla to the Pituitary Podcast. She is the director of The Duke Pituitary Program. Today she joins PWN co-founder and medical director of the California Center for Pituitary
Tests of Pituitary Function: Cushing’s syndrome
September 28, 2025
From Lewis Blevins, MD – Cortisol is a stress hormone. Thus, physical or psychic stress can elevate cortisol levels in normal persons. Depression and alcoholism can elevate cortisol levels and cause what is called pseudo-
Postoperative Evaluation of Patients with Cushing’s Disease.
September 28, 2025
From Lewis S. Blevins Jr, MD – One of the greatest challenges facing medical practitioners is in the recognition and diagnosis of Cushing’s syndrome and disease. As if this not sufficiently difficult, an even greater
The long-term ramifications of Cushing’s
September 28, 2025
In this informative podcast, Dr. Lewis Blevins explores the long-term issues affecting people with Cushing’s disease and syndrome. For more information on Cushing’s download this series of podcasts. Music by Patrick Muecke
What to Expect after Successful Cushing’s Disease Surgery
September 28, 2025
Have you recently been scheduled for or had surgery for Cushing’s Disease? Dr. Lewis Blevins from UCSF explains what to expect here.
Podcasts series on recurring Cushing’s disease
September 28, 2025
Pituitary World News podcast series on recurring Cushing’s disease is made possible in part by a generous grant from Corcept Therapeutics This series covers the approaches, debates, evaluations, and the difficulties in diagnosis and managing
Alternative Cushing’s syndrome treatment
September 28, 2025
Grzegorz Rosiak, M.D., an interventional radiologist from Warsaw Medical University, sends us a recently published article, “Percutaneous Adrenal Gland Thermal Ablation,” an alternative Cushing syndrome treatment. You can read more about thermal ablation of the adrenal gland